Endocrine Abstracts

Female adrenal failure involves impaired DHEA secretion and very low circulating androgens. To address the impact of a daily physiological substitution dose of capsule DHEA 50 mg on quality of life and sexual parameters, we performed a 6 month trial in a randomised, crossover and placebo controlled design. The trial was approved by the local ethical committee and conducted according to GCP guidelines. Ten patients were enrolled. Seven patients reported seborrhoic side effects ...